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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Cialis and Other Medicines:

Cialis, also known by its generic name tadalafil, is a prescription medication for treating erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It is available in various* brand and generic forms, and the generic name is tadalafil. While Cialis is frequently used as a treatment for ED and PPH, it is not a controlled substance for all individuals. Here are the key drug-drug interactions:

  1. Nitrates: This medication is used to treat high blood pressure, and it can cause a sudden drop in blood pressure that can be a severe side effect for individuals with certain health conditions. It can be used at any time, and it is usually not recommended to take it with nitrates or nitric oxide donors. However, if you take nitrates or nitric oxide donors, it is recommended to avoid using Cialis with nitrates or nitric oxide donors.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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  • These conditions may affect your health.

    As with all prescription medications, inform your doctor of any medical conditions liability for any adverse reactions if you experience these.

    Know And Follow How to Use Cialis:

    If you're experiencing a reaction to this medication, contact your health care provider right away. They mayvised to send you a sample of their dosing schedule.

    If you don't see any changes, contact your doctor.

    In the event that you don't see any changes, you may need to condos you already have or call your doctor.

    If you have not received a Dosing Event, you will need to provide your doctor with a dosing schedule.

    Alternatively, you canindal help men with erectile dysfunction and their partners to get a Dose for ED.

    Alternatively, this medication can be prescribed to treat Erectile Dysfunction by treating the symptoms.

    Alternatively, this medication can be prescribed to treat impotence by treating the sexual side effects.

    Alternatively, this medication can be prescribed to treat ED by treating the symptoms.

    Alternatively, this medication can be prescribed to treat impotence by treating the symptoms.

    Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.

    Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

    Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.

    If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.

    For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:

    • You may take it as needed, usually at least 30 minutes before sexual activity, with its effects potentially lasting up to 36 hours.
    • Your doctor may recommend taking generic Cialis regularly, once a day.

    Follow your doctors instructions carefully based on your specific needs and condition.

    If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.

    Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.

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    As with any medication, there may be side effects. Some possible side effects of Tadalafil generic are: • Headache. • Flushing. • Nasal congestion. • nasal congestion. • Upset stomach. • Stuffy nose. • Dizziness. • Stomach cramps. • Muscle pain. • Injection fever. • Headache. • Dental pain. • Dyspnea. • Heartburn. • Severe headache. • Muscle weakness.

    As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. Daily Tadalafil use is usually associated with lower incidents and severity of side effects compared to as-needed Tadalafil dosing.

    Most common Tadalafil side effects

    • Headache
    • Indigestion
    • Back pain
    • Muscle pain
    • Flushing
    • Stuffy nose

    Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

    • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
    • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
    • Sudden hearing decrease or hearing loss. Some may also have ringing in the ears (tinnitus) or dizziness.

    For a complete list of possible side effects,.

    Possible drug interactions

    Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

    On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

    For a complete list of possible drug interactions,.

    Other important safety information

    Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

    After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

    Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or healthcare provider.

    Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    How do I use Tadalafil?

    The recommended dose of Tadalafil is one tablet taken orally in the morning or one tablet in the afternoon. The recommended dose of Tadalafil for pulmonary arterial hypertension is one tablet taken orally in the morning. Patients should take Tadalafil 1-2 hours before or after they take any other medication. There may be a possibility of fainting or light-headedness when taking Tadalafil.